INSTITUT FÜR BIOMETRIE UND MEDIZINISCHE INFORMATIK

Publikationen

Bücher/Buchkapitel

  1. U. Bommerich, J. Bernarding, D. Lego, T. Trantzschel, M. Plaumann

Buchkapitel 3: “Hyperpolarization for signal enhancement in fluorine MR applications“ im Buch: “19F Magnetic Resonance Imaging” von Erich Ahrens und Ulrich Flögel, Pan Stanford Verlag, 2016.

Artikel

  • T. Trantzschel, J. Bernarding, M. Plaumann, D. Lego, T. Gutmann, T. Ratajczyk, S. Dillenberger, G. Buntkowsky, J. Bargon, U. Bommerich

Parahydrogen induced polarization in face of keto-enol tautomerism: proof of concept with hyperpolarized ethanol, Phys. Chem. Chem. Phys., 2012, 14:5601-5604.

DOI: 10.1039/C2CP40272F.

  • T. Trantzschel, M. Plaumann, J. Bernarding, D. Lego, T. Ratajczyk, S. Dillenberger, G. Buntkowsky, J. Bargon, U. Bommerich

Application of Parahydrogen-Induced Polarization to Unprotected Dehydroamino Carboxylic Acids, Appl. Magn. Reson. 2013, 44:267-278.

DOI: 10.1007/s00723-012-0391-0.

  • M. Plaumann, U. Bommerich, T. Trantzschel, D. Lego, S. Dillenberger, G. Sauer, J. Bargon, G. Buntkowsky, J. Bernarding

Parahydrogen-Induced Polarization Transfer to 19F in Perfluorocarbons for 19F NMR and MRI, Chemistry – A European Journal 2013, 19:6334-6339.

DOI: 10.1002/chem.201203455.

  • D. Lego, M. Plaumann, T. Trantzschel, J. Bargon, H. Scheich, G. Buntkowsky, T. Gutmann, G. Sauer, J. Bernarding, U. Bommerich

PHIP of carboxylic acids: A pilot study to hyperpolarize valproic acid and related structures, NMR in Biomedicine, 2014, 27:810-816.

DOI: 10.1002/nbm.3123.

  • G. Buntkowsky, T. Gutmann, M.V. Petrova, K.L. Ivanov, U. Bommerich, M. Plaumann, J. Bernarding

Dipolar Induced Para-Hydrogen-Induced Polarization, Solid State Nuclear Magnetic Resonance, 2014, 63-64:20-29.

DOI: 10.1016/j.ssnmr.2014.07.002.

  • K. Buckenmaier, M. Rudolph, C. Back, T. Misztal, U. Bommerich, P. Fehling, D. Koelle, R. Kleiner, H. A. Mayer, K. Scheffler, J. Bernarding, M. Plaumann

SQUID-based detection of ultra-low-field multinuclear NMR of substances hyperpolarized using signal amplification by reversible exchange,
Scientific Reports, 2017, 7, Art. Nr. 13431.

DOI: 10.1038/s41598-017-13757-7.

  • J.-B. Hövener, A. N. Pravdivtsev, B. Kidd, C. R. Bowers,S. Glöggler, K. V. Kovtunov, M. Plaumann, R. Katz-Brull, K. Buckenmaier, A. Jerschow, F. Reineri, T. Theis, R. V. Shchepin, S. Wagner, P. Bhattacharya, N. M. Zacharias, E. Y. Chekmenev

Parahydrogen-based Hyperpolarization for Biomedicine, Angew. Chem. – Int. Ed., 2018, 57(35):11140-11162.

DOI: 10.1002/anie.201711842.

  • J.-B. Hövener, A. N. Pravdivtsev, B. Kidd, C. R. Bowers,S. Glöggler, K. V. Kovtunov, M. Plaumann, R. Katz-Brull, K. Buckenmaier, A. Jerschow, F. Reineri, T. Theis, R. V. Shchepin, S. Wagner, P. Bhattacharya, N. M. Zacharias, E. Y. Chekmenev

Parawasserstoff-basierte Hyperpolarisierung für die Biomedizin, Angew. Chem., 2018, 130:11310-11333.

DOI: 10.1002/ange.201711842. 

  • J. Bernarding, F. Euchner, C. Bruns, R. Ringleb, D. Müller, T. Trantzschel, J. Bargon, U. Bommerich, M. Plaumann

Low-cost LED-based photo-CIDNP enables biocompatible hyperpolarization of 19F for NMR and MRI at 7 T and 4.7 T, ChemPhysChem, 2018, 19(19):2453-2456.

DOI: 10.1002/cphc.201800570.

  • J. G. Skinner, L. Menichetti, A. Flori, A. Dost, A. Schmidt, M. Plaumann, F Gallagher, J.-B. Hövener

Metabolic and Molecular Imaging with Hyperpolarised Tracers, Molecular Imaging and Biology, 2018, 20:902-918.

DOI: 10.1007/s11307-018-1265-0.

  • K. Buckenmaier, M. Rudolph, T. Steffen, P. Fehling, C. Back, R. Bernard, R. Pohmann, J. Bernarding, R. Kleiner, D. Koelle, M. Plaumann, K. Scheffler

Mutual benefit achieved by combining ultralow-field magnetic resonance and hyperpolarizing techniques

Review of Scientific Instruments, 2018, 89:125103.

DOI: 10.1063/1.5043369.

  • S. Hadjiali, R. Savka, M. Plaumann, U. Bommerich, S. Bothe, T. Gutmann, T. Ratajczyk, J. Bernarding, H.‑H. Limbach, H. Plenio, G. Buntkowsky

Substituent Influences on the NMR Signal Amplification of Ir Complexes with Heterocyclic Carbene Ligands, Appl Magn Reson, 2019, 50:895–902.

DOI: 10.1007/s00723-019-01115-x.

  • K. Buckenmaier, K. Scheffler, M. Plaumann, P. Fehling, J. Bernarding, M. Rudolph, C. Back, D. Koelle, R. Kleiner, J.-B. Hövener, A. N. Pravdivtsev

Multiple Quantum Coherences Hyperpolarized at Ultra‐Low Fields, ChemPhysChem, 2019, 20(21):2823-2829.

DOI: 10.1002/cphc.201900757.

  • S. Hadjiali, M. Bergmann, A. Kiryutin, S. Knecht, G. Sauer, M. Plaumann, H.-H. Limbach, H. Plenio, G. Buntkowsky

The application of novel Ir-NHC polarization transfer complexes by SABRE, J. Chem. Phys., 2019, 151:244201.

DOI: 10.1063/1.5128091

Konferenzbeiträge

  • U. Bommerich, M. Plaumann, T. Trantzschel, J. Bargon, G. Buntkowsky, J. Bernarding

First step of 19F Hyperpolarization of Biocompatible Substrates Generated via Parahydrogen-Transfer

Proc. Intl. Soc. Mag. Reson. Med. 2011, 19, 1521

  • U. Bommerich, M. Plaumann, D. Lego, T. Trantzschel, J. Bernarding

Generating 19F Hyperpolarized Semifluorinated alkanes via Parahydrogen-Transfer

SCM  2011,#06, Noordwijk (Niederlande)

  • T. Trantzschel, U. Bommerich, M. Plaumann, D. Lego, T. Ratajczyk, T. Gutmann, S. Dillenberger, G. Buntkowsky, J. Bargon, J. Bernarding

Biocompatible 19F Hyperpolarized Semifluorinated alkanes generated via PHIP

ESMRMB 2011, #520, Leipzig (Deutschland)

  • T. Trantzschel, U. Bommerich, M. Plaumann, D. Lego, T. Gutmann, T. Ratajczyk, S. Dillenberger, G. Buntkowsky, J. Bargon, J. Bernarding

Synthesis of hyperpolarized Ethanol via PHIP

Proc. Intl. Soc. Mag. Reson. Med. 2012, 20, 1678

  • M. Plaumann, J. Bernarding, D. Lego, T. Trantzschel, C. Köhn, S. Dillenberger, T. Gutmann, T. Ratajczyk, J. Bargon, G. Buntkowsky, U. Bommerich

New strategy to hyperpolarize biological relevant molecules containing free amino-groups

ESMRMB 2012, #222, Lissabon (Portugal); EPOS zusätzlich zum Vortrag

  • M. Plaumann, U. Bommerich, T. Trantzschel, D. Lego, S. Dillenberger, J. Bargon, G. Buntkowsky, J. Bernarding

Hyperpolarization of biologically relevant compounds which are important in the GABA metabolism

Proc. Intl. Soc. Mag. Reson. Med. 2013, 21, 3927

  • M. Plaumann, T. Trantzschel, D. Lego, G. Sauer, T. Gutmann, J. Bargon, G. Buntkowsky, J. Bernarding, U. Bommerich

Hyperpolarized Fluorinated Amino Acid as NMR-based Biomarker

ESMRMB 2013, #471, Toulouse (Frankreich); EPOS zusätzlich zum Vortrag

  • M. Plaumann, T. Trantzschel, D. Lego, C. Köhn, G. Sauer, T. Gutmann, J. Bargon, G. Buntkowsky, U. Bommerich, J. Bernarding

Hyperpolarization of a bisfluorinated phenylalanine derivative using PHIP and examination of the interaction with β-cyclodextrin

Proc. Intl. Soc. Mag. Reson. Med. 2014, 22, 2780

  • T. Trantzschel, D. Lego, M. Plaumann, G. Sauer, T. Gutmann, J. Bargon, G. Buntkowsky, J. Bernarding, U. Bommerich

PHIP of valproic acid and related structures

Proc. Intl. Soc. Mag. Reson. Med. 2014, 22, 2781

  • C. Köhn, T. Trantzschel, M. Plaumann, U. Bommerich, D. Lego, J. Bernarding

Field dependency of Parahydrogen Induced Hyperpolarization (PHIP) of 1H and 19F in Earth’s Magnetic Field

Proc. Intl. Soc. Mag. Reson. Med. 2014, 22, 2784

  • M. Plaumann, D. Lego, T. Trantzschel, J. Wüstemann, G. Sauer, T. Gutmann, G. Buntkowsky, J. Bargon, J. Bernarding, U. Bommerich

19F-Kernspinhyperpolarisation linearer und verzweigter Alkane

DS-ISMRM 2014, Jena (Deutschland), P05

  • M. Plaumann, J. Wüstemann, D. Lego, T. Trantzschel, G. Sauer, T. Gutmann, G. Buntkowsky, J. Bargon, J. Bernarding, U. Bommerich

Parahydrogen Induced Polarization of fluorinated substrates for 19F MR spectroscopy and imaging

EMIM 2015, #127, Tübingen (Deutschland)

  • U. Bommerich, T. Trantzschel, M. Plaumann, D. Lego, G. Buntkowsky, G. Sauer, T. Gutmann, J. Bargon, J. Bernarding

19F-Hyperpolarized Structures as Marker for the Improved Detection of Amyloid Plaques

Proc. Intl. Soc. Mag. Reson. Med. 2015, 1878

  • M. Plaumann, T. Trantzschel, J. Wüstemann, D. Lego, G. Sauer, T. Gutmann, J. Bargon, G. Buntkowsky, J. Bernarding, U. Bommerich

PHIP hyperpolarization of linear and branched fluorinated alkanes as well as their interaction with cyclodextrins

Proc. Intl. Soc. Mag. Reson. Med. 2015, 1879

  • M. Plaumann, D. Lego, T. Trantzschel, J. Wüstemann, G. Sauer, T. Gutmann, G. Buntkowsky, J. Bargon, U. Bommerich, J. Bernarding

Parahydrogen Induced Polarization (PHIP) of anticancer drug substructures

GDCh – FGMR 2015, #78, Darmstadt (Deutschland)

  • F. Euchner, U. Bommerich, R. Ringleb, J. Bargon, J. Bernarding, M. Plaumann

PHIP of fluorinated quaternary pyridinium ions

EMIM 2016, #92, Utrecht (Niederlande)

  • M. Plaumann, T. Trantzschel, J. Bargon, U. Bommerich, J. Bernarding

LED induced 19F MR signal enhancement at 7T

Proc. Intl. Soc. Mag. Reson. Med. 2016, 3684

  • F. Euchner, R. Ringleb, J. Bargon, U. Bommerich, J. Bernarding, M. Plaumann

First hyperpolarization of quaternary pyridinium salts using PHIP

Proc. Intl. Soc. Mag. Reson. Med. 2016, 3688

  • F. Euchner, U. Bommerich, T. Trantzschel, J. Bargon, M. Plaumann, J. Bernarding

LED induced 19F hyperpolarization in physiological solvent

ESMRMB 2016, #155, Wien (Österreich); EPOS zusätzlich zum Vortrag

  • M. Plaumann, F. Euchner, R. Ringleb, S. Hadjiali, J. Bargon, G. Buntkowsky, J. Bernarding, U. Bommerich

Hyperpolarization of fluorinated pyridine carboxylic acids

ESMRMB 2016, #398, Wien (Österreich); EPOS zusätzlich zum Vortrag

  • F. Euchner, U. Bommerich, R. Ringleb, J. Bargon, M. Plaumann, J. Bernarding

Hyperpolarization of two tyrosine derivatives using photo-CIDNP

EMIM 2017, #164, Köln (Deutschland)

  • K. Buckenmaier, M. Rudolph, C. Back, J. Engelmann, J. Rudin, T. Misztal, U. Bommerich, K. Scheffler, D. Koelle, R. Kleiner, H. Mayer, J. Bernarding, M. Plaumann

SQUID based Ultralow field nuclear magnetic resonance spectroscopy using the pH2 based hyperpolarization technique SABRE

Proc. Intl. Soc. Mag. Reson. Med. 2017, 3033, Honolulu (USA)

  • F. Euchner, M. Plaumann, T. Trantzschel, J. Bargon, U. Bommerich, J. Bernarding

photo-CIDNP for 19F MR amino acid-protein interaction studies in physiological solvents

Proc. Intl. Soc. Mag. Reson. Med. 2017, 3036, Honolulu (USA)

  • M. Plaumann, F. Euchner, R. Ringleb, S. Hadjiali, J. Bargon, G. Buntkowsky, J. Bernarding and U. Bommerich

Examination of the hyperpolarizability of fluorinated nicotinic acids and further pyridine carboxylic acids using SABRE

Proc. Intl. Soc. Mag. Reson. Med. 2017, 3038

  • D. Müller, F. Euchner, R. Ringleb, U. Bommerich, J. Bargon, G. Buntkowsky, J.  Bernarding, M. Plaumann

Positive charged nitrogen atom influences polarization transfer in PHIP experiments

GDCh – FGMR 2017, P. 109, Bayreuth (Deutschland)

  • M. Plaumann, R. Ringleb, F. Euchner, S. Hadjiali, J. Bargon, U. Bommerich, G. Buntkowsky, J. Bernarding

1H, 13C and 19F hyperpolarization of three substituted pyridine derivates

ESMRMB 2017, angenommen, Barcelona (Spanien)

  • M. Plaumann, K. Buckenmaier, S. Hadjiali, F. Euchner, M. Rudolph, R. Ringleb, U. Bommerich, J. Bargon, G. Buntkowsky, K. Scheffler, J. Bernarding,

Signal detection of 19F hyperpolarized pyridine derivatives at low and at high magnetic field strengths

Red Hot MRI: Fluorine Imaging, An informal symposium to discuss and foster collaborative 19F MRI, 2017, S.25, Berlin (Deutschland)

  • F. Euchner, C. Bruns, R. Ringleb, J. Bargon, M. Plaumann, J. Bernarding

Comparison of the hyperpolarization of different fluorinated aromatic systems via photo-CIDNP

HYP18 – Hyperpolaried Magnetic Resonance, 2018, P48, Southampton (England)

  • M. Plaumann, F. Euchner, R. Ringleb, S. Hadjiali, J. Bargon, U. Bommerich, G. Buntkowsky, J. Bernarding

SABRE-based hyperpolarization and substituent effects

HYP18 – Hyperpolaried Magnetic Resonance, 2018, P104, Southampton (England)

  • F. Euchner, C. Bruns, R. Ringleb, J. Bargon, J. Bernarding, M. Plaumann

LED-based photo-CIDNP increases 19F signal for MRI

GDCh – FGMR 2018, #093, Leipzig (Deutschland)

  • M. Plaumann

19F MR Hyperpolarization – Hyperpolarization in aqueous solutions

EMIM – Study Group “Hyperpolarized MRI”, 2018, San Sebastián (Spanien)

  • K. Buckenmaier, M. Rudolph, P. Fehling, C. Back, J. Bernarding, D. Kölle, R. Kleiner, K. Scheffler, M. Plaumann

SQUID based magnetic resonance imaging for the investigation of in situ and in vivo hyperpolarization techniques

EMIM, 2018, PS-13-2, San Sebastián (Spanien)

  • M. Plaumann

Boosting 19F MRI Sensitivity by Hyperpolarization

ISMRM, 2018, MIS-10, Paris (Frankreich)

  • F. Euchner, C. Bruns, R. Ringleb, J. Bargon, M. Plaumann, J. Bernarding

Comparison of the hyperpolarization of different fluorinated aromatic systems via photo-CIDNP

HYP18 – Hyperpolaried Magnetic Resonance, 2018, P48, Southampton (England)

  • M. Plaumann, F. Euchner, R. Ringleb, S. Hadjiali, J. Bargon, U. Bommerich, G. Buntkowsky, J. Bernarding

SABRE-based hyperpolarization and substituent effects

HYP18 – Hyperpolaried Magnetic Resonance, 2018, P104, Southampton (England)

  • F. Euchner, C. Bruns, R. Ringleb, J. Bargon, J. Bernarding, M. Plaumann

 LED-based photo-CIDNP increases 19F signal for MRI

 GDCh – FGMR 2018, #093, Leipzig (Deutschland)

  • M. Plaumann

Hyperpolarisation mittels Parawasserstoff (PHIP&SABRE)

49. Jahrestagung der DGMP & 21. Jahrestagung der DS-ISMRM, 2018, FS 23, Nürnberg (Deutschland)

  • F. Euchner, R. Ringleb, C. Bruns, J. Bargon, J. Bernarding, M. Plaumann,

Examination of photo-CIDNP based 19F hyperpolarization in dependence of the temperature

EMIM, 2019, #740, Glasgow (Schottland)

  • K. Buckenmaier, M. Rudolph, A. Pravdivtsev, P. Fehling, T. Steffen, C. Back, R. Bernard, R. Pohmann, J. Bernarding, R. Kleiner, D. Koelle, J. Hövener, K. Scheffler, M. Plaumann

Advantages of combining nuclear magnetic hyperpolarization and ultralow-field magnetic resonance

21st ISMAR-15th EUROMAR Jount Conference, 2019, #553, Berlin (Deutschland)

  • M. Plaumann, F. Euchner, C. Bruns, J. Bernarding

Hyperpolarisation fluorierter Phenolderivate in wässriger Lösung

DS-ISMRM 2019, Bd. 22, S. 88-89, Kiel (Deutschland)

  • R. Ringleb, F. Euchner, S. Hadjiali, U. Bommerich, C. Bruns, J. Bargon, G. Buntkowsky, J. Bernarding, M. Plaumann

Complex selection determines phases of 1H and 19F MR signals in SABRE-based hyperpolarization

ESMRMB 2019, Magnetic resonance materials in physics, biology and medicine - Heidelberg: Springer, Bd.32, Suppl. 1, S10.06, S. S127, Rotterdam (Niederlande)

 

 

 

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