Markus Plaumann
- Management of the lab for the synthesis, cell culture and NMR ("Haus 28")
- Management of the Data Trust
- Teaching coordination of Biometry and Medical Informatics
Professional career
2006 Diplom in Chemistry (University of Bremen)
2010 Doctorate (University of Bremen)
Projects
- Data Trust Association Biomedical Research Data State of Saxony-Anhalt [01.01.2022 to 31.12.2024]
- Independent parahydrogen-induced two-phase hyperpolarizer for ultra-low field and ultra-high field MR (2P-PHIP) [01.01.2022 to 31.12.2024]
- Construction of an LED unit for light-induced hyperpolarization of physiological substances [02.01.2018 to 31.12.2023].
Completed projects
- Development of molecular MR temperature probes
- Fluorinated boron clusters in cell culture
- Parahydrogen-induced nuclear spin hyperpolarization of fluorinated substrates - standard PHIP
- Parahydrogen-induced nuclear spin hyperpolarization - studies using the SABRE method
- Enhancement of MR sensitivity of 19F biomarkers and PET-analogous 19F-labeled receptor ligands by para-hydrogen-induced polarization
Research focus
19F NMR spectroscopy and MR imaging
- Enhancement of MR signals by parahydrogen-induced hyperpolarization (PHIP: PASADENA, ALTADENA, SABRE) and photo-CIDNP
- Cell labeling with MR-sensitive fluorinated substances for non-invasive observation of cell migration in tumor treatment
- Temperature determination using fluorinated markers and MR spectroscopy
- Synthesis and characterization of new water-soluble fluorinated compounds
Viability measurements in cell culture
- Review of the toxicity and stability of organic compounds regarding their toxicity and stability on fibroblasts and melanoma cells
- Lecture and seminar Q1 Medical Informatics (further Information: Moodle)
- Lecture/Exercise: "Medicinal Chemistry" at the University of Bremen
- Practical course: "Structure elucidation of organic compounds" at the University of Bremen