News
DataDay: Insights into the World of Data Trustees
Data are essential for science and research. Data trust structures such as the data trust (THS) at IBMI come into play to protect them. At DataDay on 30 June 2023, our colleagues learned about and discussed opportunities for data trusteeship.
Speakers, such as our former intern Hanna Püschel, among others, provided insights into how legal scholars evaluate the idea of a data trust and how data intermediaries are used in medicine, among other fields.
Publication: ATLAS non-interventional study
This single-visit, cross-sectional, non-interventional study in adults was to characterize the sensitization to allergens in severe asthma (independent of phenotype). Out team member Anke Lux participated by providing biometric consultation. Find out more about the study here.
Publication: "Subjective well-being of employees in the emergency services with different work-related behavior and experience patterns"
The emergency services are often faced with patients suffering from psychological distress. This survey explored connections between subjective wellbeing and patterns of work-related behavior and experience, in order to identify areas of intervention for health promotion services. Our colleague, Anke Lux, collaborated in the study. You can read more about it here.
DataDay: Insights into the World of Data Trustees
Data are essential for science and research. Data trust structures such as the data trust (THS) at IBMI come into play to protect them. At DataDay on 30 June 2023, our colleagues learned about and discussed opportunities for data trusteeship.
Speakers, such as our former intern Hanna Püschel, among others, provided insights into how legal scholars evaluate the idea of a data trust and how data intermediaries are used in medicine, among other fields.
Publikation: "Measurement and advanced data post-processing of proton resonance frequency shift in 7 T MRI to obtain local temperature in a tissue-mimicking phantom"
In der Zeitschrift tm - Technisches Messen wurde oben genannte Publikation am 09. August 2024 unter Mitwirkung der Co-Autoren Prof. Dr. Dr. Johannes Bernarding und Christian Bruns veröffentlicht. Für nähere Informationen siehe diesen Link.
Abstract
The radio-frequency (RF) transmit power deposition in tissue during magnetic resonance imaging (MRI) at ultra-high fields, i.e. B 0 ≥ 7 T, is a major challenge for pulse sequences requesting large flip angles. The absorbed RF energy can pose safety risk to patients as it is rising temperature in the tissue. The temperature can be accessed using MRI itself via the proton-resonance frequency (PRF) shift technique, which at low B 0 has been shown a valid MR thermometry method. In this paper, we explore the applicability of the PRF method to the assessment of local temperature in 7 T MRI procedures. To this end, we built a phantom filled with a material presenting electrical conductivity and permittivity close to muscle tissue. Tubes filled with oil were placed nearby the phantom to observe the time dependent B 0 drift. MRI phase images were acquired by gradient-echo (GRE) sequences at time points between spin-echo sequences with large flip angle allowing for a continuous assessment of the temperature during a 114 min RF-heating experiment. All acquired phase images were post-processed with attention to the time dependent instability of B 0, and, in addition, to potential spatial and temporal phase discontinuities, known as wraps. In this paper, we present a strategy to analyze and to unfold these phase wraps for large measurement fields and long acquisition times. It is shown that the PRF shift method is beneficial for the assessment of temperature at 7 T MRI. The temperature maps for axial and coronal planes display a temperature increase of approximately 3.5 °C during the time of the RF-heating experiment. Overall it is shown that B 0-drift correction and, importantly, the spatio-temporal unwrapping are an indispensable part of post-processing.